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clock.bio has developed a proprietary system to force human iPSCs to age in vitro, then uses genome-wide CRISPR screens to identify genes that drive self-rejuvenation. They have created an "Atlas of Rejuvenation Factors" with over 100 gene targets. The company recently raised $5.3M seed funding to validate these findings and prioritize therapeutic leads for future clinical translation. No clinical results reported yet.
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