Company intelligence / Profile preview

Codexis, Inc.

Redwood City, California, United Statescodexis.com ↗

Ownership: Public · CDXS
Employees: ~332
Development stage: Commercial

Overview

Codexis is a leader in enzyme engineering with its CodeEvolver® platform. Its engineered enzymes have enabled the efficient manufacture of blockbuster pharmaceuticals such as Januvia®, Lipitor®, and Paxlovid®. The company is now focused on enabling scalable enzymatic siRNA manufacturing through its ECO Synthesis™ platform. Clinical results pertain to partner programs using Codexis technology rather than direct therapeutic assets owned by Codexis itself[2][3].

Therapeutic areas: Metabolic Disorders
Modalities: Enzymes (biocatalysts)Oligonucleotides (siRNA manufacturing)Proteins (engineered for therapeutics manufacturing)
Industry: Non-Drug Biotech

Drug pipeline

3 assets

CDX-7108

Phase 1

Indications: Exocrine Pancreatic Insufficiency

2 more assets in the full pipeline.

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Partnerships

Merck & Co. – biocatalysis partnership for Januvia® production[2][3]Pfizer – biocatalysis partnership for Paxlovid® production [2]Takeda Pharmaceutical – gene therapy/enzyme research collaboration [3]Tate & Lyle – food ingredient R&D partnership [3]Nestlé Health Science – licensing agreement on PAL enzyme [3]Molecular Assemblies – DNA synthesis enzyme engineering [3]

Financials

Market cap: $153.8M
Total revenue: $14.9M
Enterprise value: $171.5M

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