Cogent Neuroscience

Cogent Neuroscience was a private Durham, North Carolina biotechnology company focused on discovering therapeutics for neurological and neurodegenerative diseases. Founded in 1998 by Duke University researchers Lawrence Katz and Donald Lo together with biotechnology entrepreneur Max Wallace, the company built neurogenomic discovery platforms described as Neural Tissue Transgenesis and Gene Rover to identify neuroprotective genes, proteins, and small-molecule leads. Its historical pipeline and research efforts spanned stroke, traumatic brain injury, Huntington's disease, Parkinson's disease, Alzheimer's disease, glaucoma, macular degeneration, and related retinal disorders. Available business registry and company-profile sources indicate the company is no longer active and is generally classified as dead/closed rather than acquired.