Collaborative Study Group

The Collaborative Study Group (CSG) is an independent clinical research organization (CRO) and academic consortium specializing in the design, management, and analysis of large-scale, multicenter clinical trials. Based in Chicago, the group is internationally renowned for its landmark contributions to nephrology, particularly for conducting the pivotal trials that established ACE inhibitors and ARBs as the standard of care for diabetic kidney disease. CSG provides a full suite of clinical trial services, including protocol design, site monitoring, data management, and statistical analysis. The organization primarily partners with major pharmaceutical companies to evaluate therapeutic interventions for renal, cardiovascular, and metabolic disorders. Its work has significantly influenced global clinical guidelines and the regulatory approval of several blockbuster drugs.