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Colossal Biosciences

Ownership: Private
Employees: ~170
Development stage: Preclinical

Overview

Colossal Biosciences has made significant progress toward its goal of de-extincting the woolly mammoth, Tasmanian tiger/thylacine, and dodo. The company claims to have completed genome mapping for these species and achieved key breakthroughs such as generating induced pluripotent stem cells from ancient DNA. In April 2025 it announced the world’s first successful birth of an extinct species using its technology. Its work remains pre-commercial but has attracted substantial investment due to potential applications across conservation biology and biotechnology more broadly.

Therapeutic areas: Other
Modalities: Gene editing (CRISPR)Synthetic biology platformsGenomic modeling softwareInduced pluripotent stem cells (iPSC)Artificial reproductive technologies (e.g., artificial wombs)
Industry: Non-Drug Biotech

Partnerships

Baylor College of Medicine (elephant herpesvirus research)Biorescue consortium for northern white rhino rescue missionvarious academic collaborations

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