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Constant Therapeutics LLC
Boston, Massachusetts, United Statesconstanttherapeutics.com ↗
- Ownership
- Private
- Development stage
- Phase 2
01
Overview
Constant Therapeutics LLC develops peptide and small molecule drugs targeting the alternative renin angiotensin system. Its lead candidate TXA127 entered a phase 2 trial in March 2024 for Duchenne Muscular Dystrophy-associated cardiomyopathy. The company also pursues treatments for ischemic stroke recovery and has additional preclinical programs in metabolic and rare diseases. The company’s approach centers on activating the Mas/MrgD receptors to counteract classical RAS effects implicated in cardiovascular and metabolic disorders. Early clinical results are pending from ongoing studies.[1][5]
- Therapeutic areas
- CardiovascularNeurologyMetabolic Disorders
- Modalities
- Peptides (notably synthetic peptides)Small molecules[1][6]
- Industry
- Biotech
02
Drug pipeline
2 assets1 more asset in the full pipeline.
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Partnerships
Collaborations with Columbia University noted as sponsor/collaborator on some trials/programs.[6]
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