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Constellation Pharmaceuticals is a clinical-stage biopharmaceutical company specializing in the development of small molecule therapeutics that target epigenetic regulators. The company's research focuses on modulating gene expression to treat cancer and other serious diseases, leveraging its proprietary epigenetics platform. Its lead candidate, pelabresib (CPI-0610), is a selective BET inhibitor currently in Phase 3 clinical trials for the treatment of myelofibrosis. Constellation was acquired by MorphoSys in 2021 for approximately $1.7 billion, and subsequently became part of Novartis following Novartis's acquisition of MorphoSys in 2024.
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