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CoreValve

Irvine, California, United States
Ownership
Private
Development stage
Other
01

Overview

CoreValve was a cardiovascular medical device company that developed catheter-based transcatheter aortic valve replacement technologies for patients with severe aortic stenosis and related aortic valve disease. Founded in 2001 by cardiac surgeon Jacques Seguin, the company pioneered a self-expanding prosthetic aortic valve system designed to replace failing aortic valves without open-heart surgery. Its lead product platform, often referred to as the CoreValve or ReValving System, became one of the early foundational technologies in TAVR. Medtronic signed a definitive agreement to acquire CoreValve in February 2009 for an upfront payment of $700 million plus milestone-based consideration, and subsequently integrated the business into its structural heart portfolio. The legacy CoreValve technology now underpins Medtronic's Evolut TAVR franchise.

Therapeutic areas
Cardiovascular
Modalities
Device
Industry
Implantable Medical Devices

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