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Corvention was a clinical-stage biopharmaceutical company focused on developing novel therapies for cardiovascular and renal diseases. The company's lead program, CVN058, is a potent and selective non-steroidal mineralocorticoid receptor antagonist (nsMRA) designed to treat heart failure and chronic kidney disease with a reduced risk of hyperkalemia compared to traditional steroidal MRAs. Corvention was established as a portfolio company of Deerfield Management to advance cardiovascular assets. The company was eventually acquired by AstraZeneca to bolster its late-stage cardiovascular and renal pipeline.
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