Covalys Biosciences

Covalys Biosciences was a Swiss biotechnology company specializing in advanced protein labeling and imaging technologies for life science research. The company is most recognized for developing the SNAP-tag and CLIP-tag systems, which enable the specific and covalent labeling of fusion proteins with various chemical probes, such as fluorophores or biotin. These tools significantly advanced the study of protein function, localization, and dynamics within living cells and in vitro environments. Founded as a spin-off from the École Polytechnique Fédérale de Lausanne (EPFL), Covalys provided researchers with a versatile platform for high-resolution imaging and protein immobilization. In 2009, the company was acquired by New England Biolabs, which integrated the technology into its extensive portfolio of molecular biology reagents.