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Crescent Biopharma is advancing a pipeline of next-generation oncology therapeutics, including a lead bispecific antibody (CR-001) targeting PD-1 and VEGF, which is expected to enter Phase 1 trials in early 2026. Two additional antibody-drug conjugates are in discovery and pre-IND stages. Proof-of-concept clinical data for CR-001 are expected in the second half of 2026. No human clinical results have yet been reported.[1][2][4][6]
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