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Cristcot's lead product, a novel hydrocortisone acetate (HCA) suppository delivered with the Sephure® applicator, achieved positive pivotal Phase 3 results in ulcerative colitis of the rectum—meeting pre-defined outcomes for clinical response by Day 15 and remission by Day 29. The company plans an NDA submission in Q1 2025. The pipeline includes additional GI-focused programs at earlier stages[1][3][4].
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