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cTRL Therapeutics

Chicago, Illinois, United Statesctrl-tx.com ↗

Ownership: Private
Development stage: Preclinical

Overview

cTRL Therapeutics has developed a proprietary platform, IsoQore™, that enables the non-invasive extraction and expansion of rare, potent circulating T cells from blood. Their lead product candidate, cTRL‑001, aims to provide an outpatient-ready cell therapy solution for solid tumors. The company’s approach avoids the need for surgical removal of tumor tissue and seeks to overcome challenges faced by current cell therapies in solid cancers. As of late 2024/early 2025, their lead program remains preclinical with first-in-human trials anticipated in 2025[1][2][6].

Therapeutic areas: Oncology
Modalities: Cell therapy (autologous cell therapies using circulating tumor-reactive lymphocytes)
Industry: Biotech

Drug pipeline

1 asset

cTRL-001

Preclinical

Partnerships

FACIT (investment partner)Princess Margaret Cancer Centre & University Health Network/University of Toronto (academic collaborations)[2][6].

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