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Cumulative Therapeutics is a pre-clinical stage biotechnology company focused on developing novel small molecule therapies for oncology indications. The company specializes in targeting the RAS signaling pathway, specifically by disrupting protein-protein interactions that are traditionally considered undruggable. Their lead research focuses on the Grb2-SOS1 complex to inhibit downstream RAS activation in various cancers. By utilizing a proprietary discovery approach, Cumulative Therapeutics aims to address resistance in RAS-driven tumors and provide new therapeutic options for patients with solid and hematologic malignancies.
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