CureQuest Bioscience

CureQuest Bioscience is a drug discovery company focused on developing first-in-class small molecule therapeutics for oncology and inflammatory diseases. The company specializes in modulating the Pregnane X Receptor (PXR), a key regulator of xenobiotic metabolism and inflammatory responses in the gut and liver. Their lead programs include PXR antagonists designed to sensitize tumors to chemotherapy and PXR agonists aimed at treating inflammatory bowel disease (IBD) by restoring intestinal barrier function. Headquartered in Bengaluru, India, with strong academic links to the United States, CureQuest leverages deep expertise in nuclear receptor biology to address significant unmet medical needs.