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Curis's lead candidate emavusertib is an orally available small molecule IRAK4 inhibitor in Phase 1/2 trials for hematologic malignancies including AML, hrMDS, and PCNSL. The company also has a marketed product, Erivedge® (vismodegib), licensed to Genentech/Roche for advanced basal cell carcinoma. Additional pipeline assets target immune checkpoints and epigenetic regulators.
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