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Cyon developed an anti-PCSK9 antibody (LGT-209) licensed from Novartis. Phase 1 trials successfully demonstrated the drug was well-tolerated and effective in lowering cholesterol, a key mechanism expected to prevent and improve outcomes in sepsis patients[2]. The company planned to move into Phase 2 clinical trials recruiting patients early in disease to reduce sepsis-related morbidity and mortality[2].
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