Debye Scientific

Debye Scientific is a specialized contract research organization (CRO) providing high-resolution structural biology services, primarily centered on cryo-electron microscopy (cryo-EM). The company offers end-to-end solutions including protein expression, purification, grid preparation, data collection, and 3D reconstruction. By leveraging state-of-the-art electron microscopes and computational workflows, Debye Scientific enables pharmaceutical and biotechnology companies to accelerate drug discovery through structure-based drug design. Their services are critical for visualizing complex biological targets, such as membrane proteins and GPCRs, that are challenging for traditional X-ray crystallography. The firm also utilizes MicroED technology to determine structures from sub-micron sized crystals of small molecules and proteins.