Company intelligence / Profile preview

Degron Therapeutics

San Diego, California, United Statesdegrontx.com ↗

Ownership: Private
Development stage: Other

Overview

Lead program DEG6498 (HuR degrader) received FDA IND clearance in January 2025 to initiate clinical development in solid tumors. Phase 1/2 study enrollment expected to start in early 2025. WEE1 kinase degrader preclinical candidate expected to be selected in 1H 2025.

Therapeutic areas: OncologyRare DiseasesMetabolic DisordersImmunology
Modalities: Small molecule molecular glue degraders (MGDs)
Industry: Biotech

Drug pipeline

1 asset

DEG6498

Partnerships

Takeda Pharmaceutical Company Limited (multi-target collaboration announced May 2023, worth up to $1.2 billion)

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