Demand Investigators

Demand Investigators is a clinical research consortium and study group primarily known for sponsoring and conducting the DEMAND (Diastolic Heart Failure Management by Nifedipine) clinical trials. The group focuses on cardiovascular and metabolic diseases, specifically investigating the effects of calcium channel blockers like nifedipine on heart failure with preserved ejection fraction (HFpEF). Additionally, the group has conducted large-scale observational studies, such as the global DEMAND study, which evaluated the prevalence and risk factors of microalbuminuria in patients with type 2 diabetes. While acting as a formal sponsor for clinical trials, the entity is a collaborative network of academic and clinical researchers rather than a commercial pharmaceutical company.