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DiaMedica Therapeutics

Minneapolis, Minnesota, United Statesdiamedica.com ↗
Ownership
Public · DMAC
Employees
~40
Development stage
Phase 2
01

Overview

DiaMedica’s lead candidate DM199 (rinvecalinase alfa) is in Phase 2/3 trials for acute ischemic stroke and in Phase 2 for preeclampsia. The company recently dosed the first patient in its investigator-sponsored Phase 2 trial of DM199 for preeclampsia in South Africa. Topline data from Part 1A of this study are expected in the first half of 2025 to assess safety and blood pressure-lowering effects. The ReMEDy2 trial for acute ischemic stroke continues with site activations across the US and Canada; interim results are anticipated Q4 2025[5][7][8]. Preclinical work continues on DM300 for inflammatory diseases such as acute pancreatitis.

Therapeutic areas
Women's HealthGastroenterologyCardiovascular
Modalities
Large molecules (recombinant proteins), specifically recombinant human tissue kallikrein‐1 (KLK1)recombinant human ulinastatin[3][4][9]
Industry
Biotech
02

Drug pipeline

6 assets

recombinant human kallikrein 1

3

5 more assets in the full pipeline.

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03

Partnerships

Investigator-sponsored clinical collaboration with Stellenbosch University/Tygerberg Hospital, South Africa (for PE trial)[5].No major pharma partnerships disclosed as of current reporting.
04

Financials

Market cap
$355.1M
Total revenue
$0
Enterprise value
$311.8M

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