Clinical trials
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Direct Biologics' lead product, ExoFlo™, demonstrated significant survival benefit in a phase II randomized controlled trial for hospitalized patients with moderate-to-severe acute respiratory distress syndrome due to COVID. The company also received FDA clearance to initiate a phase Ib/IIa clinical trial of ExoFlo™ for medically refractory perianal fistulizing Crohn's Disease. Expanded access data show compelling results across more than one hundred subjects treated under emergency use protocols.
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