Company intelligence / Profile preview
Dolinnov
Montpellier, Occitanie, Francedolinnov.com ↗
- Ownership
- Private
- Employees
- ~8
- Development stage
- Other
01
Overview
Dolinnov is a French biotechnology company pioneering precision RNA therapeutics for the treatment of severe chronic pain. Founded in 2024 and based in Montpellier, the company is developing a proprietary lipid-conjugated antisense oligonucleotide (L-ASO) platform designed to selectively target and silence pain-driving genes directly in the dorsal root ganglion (DRG) neurons. Dolinnov's lead candidate, DOL-001, is a first-in-class non-opioid therapy that targets FXYD2, a key regulator of neuronal excitability, to normalize Na+/K+-ATPase activity and restore sensory-neuron homeostasis. By focusing on peripheral mechanisms rather than central nervous system pathways, Dolinnov's approach aims to deliver robust, long-lasting pain relief without the central toxicities or addiction risks associated with traditional opioids.
- Therapeutic areas
- NeurologyOncologyImmunologyRare Diseases
- Modalities
- Antisense oligonucleotideBiologic
- Industry
- Biotech
02
Drug pipeline
2 assets1 more asset in the full pipeline.
03
Partnerships
Inserm Transfert
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