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Domain Therapeutics is a clinical-stage biopharmaceutical company specializing in GPCR-targeted immunotherapies, with a focus on immuno-oncology. The company leverages its proprietary platform and biomarker strategy to develop first-in-class and best-in-class candidates, several of which are in clinical or preclinical development. Its lead programs are focused on overcoming resistance to current cancer immunotherapies. Domain has successfully completed a Phase 1 monotherapy dose escalation trial for its EP4 antagonist and is preparing for a Phase 2 trial in sarcoma, in collaboration with leading oncology experts[3][4][7].
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