Company intelligence / Profile preview

Dragonfly Therapeutics

Waltham/Boston area*, MA, USAdragonflytx.com ↗
Ownership
Private
Employees
~100
Development stage
Phase 2
01

Overview

Dragonfly Therapeutics has reported encouraging early clinical results for its lead TriNKET® programs. DF1001 targeting HER2 showed pharmacodynamic responses in two-thirds of patients with advanced solid tumors in a Phase 1 trial, with signs of clinical benefit and a favorable safety profile. DF9001 targeting EGFR has entered combination trials with Merck’s KEYTRUDA®, aiming to expand efficacy in EGFR-positive cancers. The company’s platforms have enabled a broad pipeline spanning oncology and autoimmune indications.

Therapeutic areas
OncologyImmunologyNeurologyHematology
Modalities
Multispecific antibodies (TriNKET® platform)Engineered cytokines (CYTOKINE platform)Protein drugsAntibodiesTrispecific killer cell engagers (TriKE)
Industry
Biotech
02

Drug pipeline

14 assets

df9001

2

13 more assets in the full pipeline.

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03

Partnerships

Bristol Myers Squibb/BMS [collaboration/licensing on immuno-oncology assets].Merck/MSD [collaboration on DF9001 + KEYTRUDA].AbbVie [immunology collaboration].Gilead Sciences [immunotherapy collaboration].

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