Company intelligence / Profile preview
Dren Bio
Foster City, California, United Statesdrenbio.com ↗
- Ownership
- Private
- Employees
- ~75
- Development stage
- Phase 1
01
Overview
Dren Bio’s lead clinical programs are:
- DR‑01, a first-in-class antibody for selective depletion of pathogenic CD8 T cells, currently in clinical evaluation for hematologic cancers and expanding into autoimmune indications.
- DR‑0201, a bispecific antibody targeting CD20 for deep B-cell depletion via myeloid cell engagement. Early clinical data show robust B-cell depletion with potential to reset the immune system. This program was acquired by Sanofi in March 2025 after promising early results.[4] The company also has multiple preclinical programs leveraging its proprietary platform across oncology, immunology, and neurology.[5]
- Therapeutic areas
- OncologyImmunology
- Modalities
- bispecific antibodiesmonoclonal antibodies (mAbs)protein engineering
- Industry
- Biotech
02
Drug pipeline
4 assets3 more assets in the full pipeline.
03
Partnerships
Novartis Pharma AG – strategic collaboration on bispecific antibodies for cancer announced July 2024Sanofi – acquisition of DR–0201 program/affiliate March–Q2’25
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