Company intelligence / Profile preview
Duality Biotherapeutics
Suzhou, Jiangsu, Chinaen.dualitybiologics.com ↗
- Ownership
- Public · 9606.HK
- Development stage
- Phase 3
01
Overview
Duality Biotherapeutics has advanced several antibody-drug conjugates into global clinical trials across more than a dozen countries with over seven candidates in the clinic. Lead asset DB‑1303 is in Phase 3 for HER2-expressing cancers with plans for accelerated approval filings as early as late 2025. Other advanced programs target B7-H3 and TROP2 with Fast Track or Breakthrough Therapy Designations from the FDA for certain indications. The company’s first-in-class autoimmune ADC program is entering human studies for lupus erythematosus.
- Therapeutic areas
- OncologyImmunology
- Modalities
- Antibody-drug conjugateBispecific monoclonal antibodyMonoclonal antibody
- Industry
- Biotech
02
Drug pipeline
16 assets15 more assets in the full pipeline.
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Partnerships
BioNTech – exclusive license/collaboration on multiple lead assets including global rights to develop/manufacture/commercialize select ADCs outside Greater China region.BeiGene – licensed rights to a candidate targeting B7-H4.Avenzo Therapeutics – exclusive global license agreement for EGFR/HER₃ bispecific ADC program.Adcendo – partnership details not fully specified but part of >$4 billion deal value across partnerships.
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