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Ducentis BioTherapeutics developed DS-234, a preclinical fusion protein agonist of the CD200 receptor aimed at restoring immune tolerance. DS-234 demonstrated favorable preclinical results across potency, efficacy, and pharmacokinetics versus comparable CD200R antibodies. No clinical data is yet available; the program was acquired specifically for its preclinical promise in atopic dermatitis and autoimmune disease.[1][5][7][8]
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