Duke Medical Research Institute

The Duke Clinical Research Institute (DCRI) is the world's largest academic clinical research organization (ARO), operating as a full-service contract research organization (CRO) within the Duke University School of Medicine. Established in 1996 and building on a legacy dating back to 1969, the institute specializes in the design, management, and analysis of multinational clinical trials across all phases (Phase I-IV). DCRI is particularly renowned for its leadership in cardiovascular research, infectious diseases, and pediatrics, and it manages several major national patient registries. By combining the clinical expertise of practicing physicians with advanced data science and a robust operational infrastructure, DCRI provides comprehensive research services to pharmaceutical, biotechnology, and government sponsors globally.