Company intelligence / Profile preview

DURECT Corporation

Cupertino, California, United Statesprnewswire.com ↗
Ownership
Public · DRRX
Development stage
Phase 3
01

Overview

Larsucosterol demonstrated positive results in the Phase IIb AHFIRM trial for severe alcohol-associated hepatitis, published in NEJM Evidence January 2025. The FDA granted Breakthrough Therapy Designation based on these data. A registrational Phase III trial design has been finalized incorporating recent feedback and data.

Therapeutic areas
GastroenterologyPsychiatryMetabolic DisordersNephrologyOncologyNeurology
Modalities
Small molecules (notably epigenetic modulators)Long-acting injectables (drug delivery platforms such as SABER®, CLOUD™)Biodegradable implants and microparticulates (historically)
Industry
Biotech
02

Drug pipeline

6 assets

methydur

3

5 more assets in the full pipeline.

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03

Partnerships

Innocoll Pharmaceuticals (POSIMIR US commercialization)Orient Pharma (Methydur)Charles River Laboratories (ALZET product line marketing agreement until divestiture)past collaborations with pharma partners on drug delivery technologies.
04

Financials

Market cap
$59.3M
Total revenue
$447K
Enterprise value
$54.6M

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