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Adagene has advanced its lead program ADG106, a fully human agonistic monoclonal antibody targeting CD137, into Phase 1 trials in both the US and China. The company’s DPL platform enables rapid generation of mono-specific and bi-specific antibodies with unique epitope targeting. Early clinical data suggest promising safety and efficacy profiles in immuno-oncology settings. Strategic collaborations are ongoing with major pharma partners such as Exelixis for masked ADC development using SAFEbody technology.
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