Dyno eCap 1
Pre-clinical- Indications
- Retinal diseases
Company intelligence / Profile preview
Dyno Therapeutics
Cambridge* / Watertown*, Massachusetts, United Statesdynotx.com ↗
- Ownership
- Private
- Employees
- ~200
- Development stage
- Preclinical
01
Overview
Dyno has demonstrated that its AI-powered CapsidMap™ platform can generate highly diverse synthetic AAV capsids with improved properties over natural variants. These advances have led to major licensing deals with top pharma companies but no direct clinical trial results from proprietary programs have been published yet. Partners are advancing these vectors into preclinical and potentially clinical development[4][9].
- Therapeutic areas
- OtherGastroenterologyRare DiseasesNeurology
- Modalities
- Adeno-associated virus (AAV) gene therapy vectors; enabling delivery of various genetic payloads including potential for CRISPR and other gene editing modalities[1][8].
- Industry
- Drug Discovery Services
02
Drug pipeline
2 assets1 more asset in the full pipeline.
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Partnerships
Roche — licensing agreement for next-generation neurological disease-targeting AAVs; option exercised January 2025[9].Novartis — collaboration on new synthetic AAV vectors for gene therapies[6][10].Sarepta Therapeutics — collaboration focused on muscle-targeted gene therapies including Duchenne muscular dystrophy applications[6][10].NVIDIA — strategic technology partnership supporting AI infrastructure needs [7].
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