E Squared Trials and Registries

E Squared Trials and Registries is a specialized clinical research organization (CRO) that provides comprehensive management services for clinical trials and patient registries, with a primary focus on pulmonary vascular diseases. The company is widely recognized for its role in developing and maintaining large-scale scientific registries, including the United States Pulmonary Hypertension Scientific Registry (USPHSR) and the US Chronic Thromboembolic Pulmonary Hypertension Registry (US-CTEPH-R). E Squared offers expertise in study design, site coordination, data management, and regulatory support, collaborating with leading academic institutions and pharmaceutical sponsors such as Bayer and Pfizer. Their work facilitates the collection of high-quality real-world evidence, including demographic, physiologic, and genomic data, to advance the understanding and treatment of rare and complex medical conditions.