Company intelligence / Profile preview

Egle Therapeutics

Paris, Franceegle-tx.com ↗
Ownership
Private
Development stage
Phase 1
01

Overview

Egle Therapeutics has advanced its lead immuno-oncology candidate, EGL‑001—a CTLA‑4/CD25 antagonist fusion protein—into a Phase I/II clinical trial for cancer. Its autoimmune disease program, EGL‑003, has completed IND-enabling studies and will enter Phase I trials in early/mid–2025. The company leverages a proprietary platform to discover and develop therapies that modulate regulatory T cells for both oncology and autoimmunity. Recent funding from France’s “France 2030” initiative supports ongoing clinical development[1][2][5].

Therapeutic areas
OncologyImmunology
Modalities
ImmunotherapiesAntibody-cytokine fusion proteins (e.g., antagonist IL‑2 mutein fused to CTLA‑4 antibody)
Industry
Biotech
02

Drug pipeline

5 assets

EGL-001

2

4 more assets in the full pipeline.

03

Partnerships

Takeda Pharmaceuticals—three-year strategic research collaboration with option agreement since June 2020[2][5].

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