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EHT Technologies developed a proprietary engineered heart tissue platform using human induced pluripotent stem cell–derived cardiomyocytes to create 3D cardiac constructs for disease modeling, cardiac safety and efficacy testing, and gene therapy applications; the platform has been validated for efficient transduction with adeno-associated virus vectors including AAV9, supporting its use in preclinical gene therapy research for conditions such as hypertrophic cardiomyopathy.[1]
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