metformin
Phase 2- Indications
- Type 2 diabetes
Company intelligence / Profile preview
Elcelyx Therapeutics
San Diego, California, United Statesprnewswire.com ↗
- Ownership
- Private
- Employees
- ~10
- Development stage
- Phase 2
01
Overview
Elcelyx’s lead candidate, Metformin DR, demonstrated statistically significant reductions in HbA1c and fasting plasma glucose compared to placebo in a large Phase IIb trial involving patients with type 2 diabetes. The product was well tolerated and showed a favorable gastrointestinal side effect profile. Its unique mechanism—targeting drug delivery to the lower small intestine—enables effective glucose lowering with minimal systemic exposure, making it especially promising for patients with renal impairment or those intolerant to standard metformin.
- Therapeutic areas
- EndocrinologyMetabolic DisordersNephrology
- Modalities
- Small molecules (notably metformin formulations)Gut Sensory Modulators
- Industry
- Biotech
02
Drug pipeline
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