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Eldec Pharmaceuticals develops novel peptide therapeutics targeting the Orai1 calcium channel for chronic lung diseases. Their lead candidate, ELD607, derived from a sequence in the C-terminal region of SPLUNC1, has demonstrated significant reversal of existing lung damage and reduction in neutrophilia and bacterial load—including methicillin-resistant S. aureus—in preclinical animal models. The approach offers a new immunomodulatory strategy for treating both inflammation-driven pulmonary disease and antibiotic-resistant infections.
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