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Empath Biosciences

Nashville, Tennessee, United Statesempathbio.com ↗

Ownership: Private
Development stage: Preclinical

Overview

Empath Biosciences is developing a proprietary drug discovery platform that leverages biodiversity from novel or understudied bacteria to identify new small molecule therapeutics. Their lead program targets F1-ATPase with glycomacrolide compounds derived from natural products. The lead asset is in IND-enabling studies with plans to enter clinical trials in 2026. The company claims its approach can triple optimized leads and improve technical/regulatory success rates over standard small-molecule discovery methods by >50%. No published clinical results yet.

Therapeutic areas: Oncology
Modalities: Small molecules (natural product-derived and engineered)Glycomacrolides (novel chemical class from natural products)
Industry: Biotech

Drug pipeline

1 asset

EB9092

Preclinical

Partnerships

No current corporate partners; has contracted CDMO/CRO services and reached term agreements for exclusive commercial license of glycomacrolide series.Supported by Vanderbilt University.

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