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Endlyz Therapeutics has emerged from stealth with a pipeline of small-molecule modulators targeting ATP13A2 and ATP10B to restore lysosomal function in Parkinson’s disease and other neurodegenerative conditions. The lead program aims to enter IND-enabling studies in 2025, supported by a $2.2M grant from the Michael J. Fox Foundation for biomarker discovery bridging preclinical and clinical development[1][3].
No clinical results have been reported yet.
The company’s approach seeks to slow or halt disease progression rather than only address symptoms.
Collaboration with KU Leuven provides access to advanced lysosomal transporter research and drug design expertise[6].
Pipeline breadth:
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