EndoFold

EndoFold is a biotechnology company focused on developing small molecule therapeutics that modulate the endoplasmic reticulum (ER) proteostasis network. Founded by world-leading experts in protein folding and the unfolded protein response (UPR), the company aims to treat diseases caused by protein misfolding and ER stress. Their platform targets key chaperones and signaling pathways within the ER to restore cellular health. EndoFold's research is particularly relevant to neurodegenerative conditions, metabolic disorders, and orphan diseases where protein quality control is compromised. The company leverages cutting-edge chemical biology to identify novel modulators of the UPR to address high unmet medical needs.