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enGene is a clinical-stage biotechnology company focused on developing next-generation non-viral gene therapies using its proprietary Dually Derivatized Chitosan (DDX) platform. The company's lead program, detalimogene voraplasmid (EG-70), is currently in a pivotal Phase 2 study for the treatment of BCG-unresponsive non-muscle invasive bladder cancer (NMIBC). By utilizing a non-viral delivery system, enGene aims to provide localized, durable expression of therapeutic proteins directly to mucosal tissues, potentially offering a safer and more accessible alternative to viral-based gene therapies. The company is headquartered in Montreal, Canada, with significant operations in Boston, Massachusetts.
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