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EngMab

Canton of Schwyz, Switzerlandgenmab.com ↗
Ownership
Private
Development stage
Preclinical
01

Overview

EngMab was a Swiss biotech company founded in Schwyz in 2013 that developed T-cell bispecific antibodies targeting BCMA and CD3 for oncology indications, primarily multiple myeloma. Its lead asset EM801/Alnuctamab advanced into early clinical trials before the company was acquired by Celgene in late 2016. The technology aimed to redirect immune cells against cancer cells expressing BCMA. After acquisition, development continued under Celgene/Bristol Myers Squibb but recent major trials have been discontinued due to business priorities.

Therapeutic areas
Oncology
Modalities
Bispecific antibodies (T-cell bispecific antibodies, TCBs)Bispecific T-cell engagers (BiTEs)
Industry
Biotech
02

Drug pipeline

1 asset

EM901

Pre-clinical
Indications
Multiple myeloma, Hematological malignancies
03

Partnerships

No major external partnerships reported prior to acquisition; post-acquisition collaborations with bluebird bio on related BCMA programs noted at parent level.

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