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Ensemble Group
Cambridge, Massachusetts, United States
- Ownership
- Private
- Employees
- ~11
- Development stage
- Other
01
Overview
Ensemble internally developed novel synthetic macrocycle drugs (Ensemblins) for undruggable targets but did not advance any in-house drugs to late clinical stage. The IL-17 antagonist program was out-licensed to Novartis; other partnerships (Pfizer, Bristol Myers Squibb, Boehringer Ingelheim, Alexion, Genentech) focused on early discovery using macrocycle libraries. No programs reached commercialization under Ensemble's control
- Therapeutic areas
- OncologyNeurologyRare DiseasesImmunology
- Modalities
- Small moleculeSynthetic macrocycle
- Industry
- Biotech
02
Partnerships
Novartis (IL-17 antagonist, strategic development and licensing)Alexion Pharmaceuticals (protein-protein interaction discovery, milestone)Boehringer Ingelheim (macrocycle partnership)Pfizer (macrocycle drug discovery, PPIs)Bristol Myers Squibb (macrocycle drug discovery, PPIs)Genentech (macrocycle drug discovery, PPIs)
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