Company intelligence / Profile preview

Ensoma

Boston, Massachusetts, USAensoma.com ↗
Ownership
Private
Employees
~100
Development stage
Preclinical
01

Overview

Ensoma develops one-time, off-the-shelf in vivo therapies that engineer hematopoietic stem cells directly within patients to create durable therapeutic effects. Their Engenious™ platform uses virus-like particles to deliver advanced gene editing tools including next-generation CRISPR technologies. The approach aims to simplify treatment logistics by avoiding ex vivo cell manipulation or myeloablative conditioning. They have demonstrated scalable manufacturing consistency and are advancing toward clinical trials with a focus on immuno-oncology and other applications.

Therapeutic areas
OncologyImmunologyHematology
Modalities
In vivo hematopoietic stem cell engineeringGene editing technologies including CRISPR-CasVirus-like particle (VLP)-based delivery systems
Industry
Biotech
02

Drug pipeline

2 assets

EN-374

Preclinical

1 more asset in the full pipeline.

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03

Partnerships

Strategic collaboration with Takeda Pharmaceutical Company focused on research payments up to $100 million plus potential milestones related to their genomic medicine platform.

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