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Enterprise Therapeutics' lead candidate, ETD001, targets the epithelial sodium channel in airway epithelium to increase hydration and clearance of mucus. A Phase 2a trial began in July 2024 for cystic fibrosis patients. The FDA granted rare pediatric designation to ETD001. Results from this study are expected in 2025. The company has raised significant funding (£26 million/$33.1 million Series B follow-on) to support ongoing trials and expanded its leadership team recently.
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