Company intelligence / Profile preview
Enthera Pharmaceuticals
Milan, Lombardia, Italyentherapharmaceuticals.com ↗
- Ownership
- Private
- Development stage
- Phase 1
01
Overview
Enthera Pharmaceuticals has completed a Phase 1a trial of its lead candidate Ent001 in healthy volunteers with positive safety results and has initiated a Phase 1b trial in patients with moderately to severely active ulcerative colitis. The company’s approach aims to restore organ function by re-establishing stem cell capabilities via inhibition of the IGFBP3/TMEM219 apoptosis pathway. Preclinical data support potential efficacy in both T1D and IBD, with plans to expand into additional indications such as fibrotic diseases. The company’s programs are protected by a broad patent portfolio and supported by strong academic collaborations.
- Therapeutic areas
- OtherGastroenterologyEndocrinology
- Modalities
- Monoclonal antibodies (mAbs)Fusion proteins
- Industry
- Biotech
02
Drug pipeline
1 asset03
Partnerships
Academic partnerships with Boston Children’s Hospital/Harvard Medical School, University of Milan, San Raffaele HospitalInvestors include Sofinnova Partners, AbbVie Ventures, Roche Venture Fund, JDRF T1D Fund
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