Company intelligence / Profile preview

Entos Pharmaceuticals

Edmonton, Alberta, Canadaentospharma.com ↗
Ownership
Private
Employees
~70
Development stage
Preclinical
01

Overview

Entos has demonstrated strong preclinical results for its Fusogenix PLV platform in delivering nucleic acids safely and effectively. Its COVID‑19 DNA vaccine candidate completed Phase II trials with high immunogenicity and safety. The company is advancing gene therapies for rare genetic diseases such as congenital generalized lipodystrophy into IND-enabling studies, with additional oncology and neurology candidates progressing through preclinical development[6][9].

Therapeutic areas
OncologyRare DiseasesNeurologyInfectious Diseases
Modalities
Gene therapyDNA vaccinemRNA vaccineSmall molecule drug (in pipeline)Prophylactic vaccine[9][10]
Industry
Biotech
02

Drug pipeline

11 assets

Covigenix VAX-002

2

10 more assets in the full pipeline.

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03

Partnerships

Eli Lilly & Co. – multi-program collaboration on PLV delivery of oligonucleotide therapeutics ($450M deal value)[3][4][10]BioMarin Pharmaceutical – agreement to use Fusogenix system for multiple genetic disease indications[10]OncoSenX – partnered on oncology gene therapies including OSX–001/OSX–002 [5]OISIN Biotechnologies – senolytic program partner [5]California Institute for Regenerative Medicine – funding support ($4M grant) [4]

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