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EpiEndo Pharmaceuticals

Ownership: Private
Employees: ~20
Development stage: Phase 1

Overview

EpiEndo’s lead asset, glasmacinal (EP395), has completed Phase 2a trials in COPD patients. The drug demonstrated good safety/tolerability over 12 weeks, reduced sputum neutrophil elastase and MPO levels, showed anti-inflammatory effects without antimicrobial resistance risk, and enhanced host defense response. Four clinical studies have been conducted to date with positive safety/pharmacology results.

Therapeutic areas: GastroenterologyPulmonology
Modalities: Small molecules (specifically, non-antibiotic macrolides called Barriolides™)
Industry: Biotech

Drug pipeline

1 asset

glasmacinal

Partnerships

AlveoliX AG – partnership to develop gut-on-chip models for ulcerative colitis research (“EpicoliX Project”).Academic collaborations implied but not detailed.

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