Company intelligence / Profile preview

EpiVario

Philadelphia, Pennsylvania, United Statesepivario.com ↗
Ownership
Private
Development stage
Preclinical
01

Overview

EpiVario develops novel small molecule therapeutics that modulate epigenetic processes involved in long-term memory formation. Their lead approach targets the enzyme ACSS2 to disrupt maladaptive memories underlying PTSD and substance use disorders. The company has received NIH grants for preclinical research into treatments for opioid, cocaine, and alcohol use disorder. They have also licensed their portfolio of ACSS2 inhibitor compounds to ReEngage Therapeutics for cancer indications.

Therapeutic areas
PsychiatryNeurology
Modalities
small molecules (specifically neuroepigenetic modulators, ACSS2 inhibitors)
Industry
Biotech
02

Drug pipeline

2 assets

MTB-9655

1

1 more asset in the full pipeline.

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03

Partnerships

ReEngage Therapeutics (licensed portfolio of ACSS2 inhibitors for oncology applications)

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