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Escala Therapeutics was a clinical-stage biopharmaceutical company focused on developing novel treatments for rare, life-threatening kidney diseases. The company's lead program was sparsentan (formerly ESCA-001), a dual-acting endothelin receptor antagonist and angiotensin receptor blocker. Sparsentan was specifically developed to treat focal segmental glomerulosclerosis (FSGS), a rare condition that often leads to end-stage renal disease. Escala was formed as a subsidiary of Retrophin (now Travere Therapeutics) to advance this specific asset through clinical development.
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